![This study identified key differences in transendocytosis by CTLA-4 when activated by CD80 and CD86 ligands; whereby CD80 binding led to targeted ubiquitination and lysosomal degradation while CD86 binding led to enhanced This study identified key differences in transendocytosis by CTLA-4 when activated by CD80 and CD86 ligands; whereby CD80 binding led to targeted ubiquitination and lysosomal degradation while CD86 binding led to enhanced](https://www.cytoskeleton.com/media/Feb_14_CS_image_2.gif)
This study identified key differences in transendocytosis by CTLA-4 when activated by CD80 and CD86 ligands; whereby CD80 binding led to targeted ubiquitination and lysosomal degradation while CD86 binding led to enhanced
![CD28 is constitutively expressed on T cells and CD86 is expressed on... | Download Scientific Diagram CD28 is constitutively expressed on T cells and CD86 is expressed on... | Download Scientific Diagram](https://www.researchgate.net/publication/7904322/figure/fig3/AS:294410890825742@1447204434354/CD28-is-constitutively-expressed-on-T-cells-and-CD86-is-expressed-on-antigen-presenting.png)
CD28 is constitutively expressed on T cells and CD86 is expressed on... | Download Scientific Diagram
![Frontiers | The Association Between CTLA-4, CD80/86, and CD28 Gene Polymorphisms and Rheumatoid Arthritis: An Original Study and Meta-Analysis Frontiers | The Association Between CTLA-4, CD80/86, and CD28 Gene Polymorphisms and Rheumatoid Arthritis: An Original Study and Meta-Analysis](https://www.frontiersin.org/files/Articles/598076/fmed-08-598076-HTML/image_m/fmed-08-598076-g001.jpg)
Frontiers | The Association Between CTLA-4, CD80/86, and CD28 Gene Polymorphisms and Rheumatoid Arthritis: An Original Study and Meta-Analysis
![Frontiers | Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells Frontiers | Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells](https://www.frontiersin.org/files/Articles/17866/fimmu-03-00027-r2/image_m/fimmu-03-00027-g008.jpg)
Frontiers | Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells
![Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis | Genome Medicine | Full Text Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis | Genome Medicine | Full Text](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs13073-020-00756-z/MediaObjects/13073_2020_756_Fig5_HTML.png)
Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis | Genome Medicine | Full Text
![3 CD80 and CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram 3 CD80 and CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram](https://www.researchgate.net/publication/274386360/figure/fig2/AS:978234644631553@1610240722589/CD80-and-CD86-deliver-bidirectional-signaling-for-the-activation-of-T-cell-and-APC.png)
3 CD80 and CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram
![Frontiers | CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4 Frontiers | CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4](https://www.frontiersin.org/files/Articles/600000/fimmu-11-600000-HTML-r1/image_m/fimmu-11-600000-g003.jpg)
Frontiers | CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4
![Figure 8 from Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells | Semantic Scholar Figure 8 from Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/1228111f410b4705b3a54a3b7690184a13b6b7f3/10-Figure8-1.png)
Figure 8 from Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells | Semantic Scholar
![CD86 signaling model. Dotted arrows indicate proposed novel signaling... | Download Scientific Diagram CD86 signaling model. Dotted arrows indicate proposed novel signaling... | Download Scientific Diagram](https://www.researchgate.net/publication/233930359/figure/fig7/AS:385221229858818@1468855306675/CD86-signaling-model-Dotted-arrows-indicate-proposed-novel-signaling-events-identified.png)